1. Signaling Pathways
  2. MAPK/ERK Pathway
  3. Ribosomal S6 Kinase (RSK)
  4. Ribosomal S6 Kinase (RSK) Inhibitors

Ribosomal S6 Kinase (RSK) Inhibitors

p70S6K

RSK1

RSK2

RSK3

RSK4

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Ribosomal S6 Kinase (RSK) Inhibitors
Product Name p70S6K RSK1 RSK2 RSK3 RSK4 Purity
BI-D1870  
RSK1
RSK2
RSK3
RSK4
99.72%
PF-4708671
S6K1, IC50: 160 nM
S6K1, Ki: 20 nM
S6K2, IC50: 65 μM
        99.85%
Carnosol    
RSK2, IC50: ~5.5 μM
    99.90%
RSK4-IN-1 TFA        
RSK4, IC50: 9.5 nM
LY-2584702 tosylate salt
p70S6K, IC50: 4 nM
        98.58%
SM1-71    
RSK2
   
LJH685  
RSK1
      99.99%
AT13148
p70S6K, IC50: 8 nM
        99.21%
LJI308  
RSK1
RSK2
RSK3
  99.07%
AT7867
p70S6K, IC50: 85 nM
        99.88%
SL 0101-1  
RSK1
      ≥98.0%
M2698
p70S6K, IC50: 1 nM
        99.87%
Pluripotin  
RSK1, IC50: 0.5 μM
RSK2, IC50: 2.5 μM
RSK3, IC50: 3.3 μM
RSK4, IC50: 10 μM
98.86%
CMK    
RSK2
    99.64%
AD80
p70S6K
        99.88%
AT7867 dihydrochloride
p70S6K, IC50: 85 nM
        99.75%
BRD7389  
RSK1, IC50: 1.5 μM
RSK2, IC50: 2.4 μM
RSK3, IC50: 1.2 μM
  99.75%
GSK-25  
RSK1, IC50: 398 nM
      99.68%
TAS0612
p70S6K
        98.70%
RSK4-IN-1        
RSK4, IC50: 9.5 nM
98.63%
FMK-MEA    
RSK2
    99.40%
S6K1-IN-1
p70S6K1, IC50: 52 nM
        99.44%
Eudesmin
p70S6K
        99.96%
Hu7691  
RSK1, IC50: 756 nM
     
LY-2584702 free base
p70S6K, IC50: 4 nM
        99.56%
MBM-55S  
RSK1, IC50: 5.4 nM
     
Hu7691 free base  
RSK1, IC50: 756 nM
     
CKI-7
p70S6K
       
RSK2-IN-2    
RSK2
RSK3
 
DD1
p70S6K
        99.40%
RSK2-IN-3    
RSK2, pIC50: 8.3 (ERK2-MSK1 cascade)
RSK2, pIC50: 9.2 (MSK1 CTKD)
   
LY-2584702 hydrochloride
p70S6K, IC50: 4 nM